Largely due to the preaching of St. Bernardino of Siena in the 1500 century the name “Jesus” was added to the Hail Mary: “Blessed is the fruit of thy womb, Jesus.
This second part (“Holy Mary, Mother of God, pray for us sinners now, and at the hour of our death”) is believed by many to have been added during the plague to ask for the Blessed Mother’s protection from the fatal disease.
An expert in Marian devotion, Fr. Donald H. Calloway, confirms this conclusion in his book Champions of the Rosary and explains how, “After the Black Death, the second half of the Hail Mary began to appear in the breviaries of religious communities.
The plague now is the loss of souls to Satan.
Then it was physical casualties now it is spiritual casualties.